Case 1: A 3 year old male with small bowel transplant for gastroschisis and resultant short bowel syndrome. The slide is from the day 0 postperfusion bowel.

Case 2: A 2 year old child status post small bowel and liver transplant for short gut syndrome and TPN induced liver damage, has fevers. Slide is from biopsy done 15 days post-transplant.

Case 3: An 8 year old girl status post small bowel transplant on FK506, now 7 and a half years post-transplant. Slide is from surveillance biopsy.

Case 4: A 4 and a half year old child status post small bowel/liver transplant about 1 and a half years ago now doing relatively well presents with episodes of tonsillitis and most recent EBV PCR levels being 330,000 in the whole blood assay. Her tacrolimus levels have been lowered recently. Allograft small bowel biopsy provided.

Case 5: A 20 year old female s/p small bowel transplant. Slide is from the graft enterectomy specimen.

Case 6: A 1 year old child s/p small bowel and liver transplant for short gut syndrome, now 2 and a half months post-transplant with increased stomal output. Endoscopy showed congested mucosa but no ulcers. Allograft small bowel biopsy provided (1 H&E slide)

Case 7: A 1 year old child with s/p liver transplant for extrahepatic biliary atresia has fever and elevated liver enzymes (SGOT 115; SGPT 137, GGT 113, Bil 1.1, FK506 level 11.1), 10 days post-transplant. Allograft liver biopsy provided. (1 H&E slide)

Case 8: 19 year old male s/p multivisceral transplant with elevated liver enzymes (SGOT 105, SGPT 52, GGT 3326, T. Bil 8.6) on FK506 (level 11.9), 3 months post-transplant. Allograft liver biopsy slide provided.

Case 9: A 1 year old girl s/p second transplant for EHBA and thrombosed artery of 1st allograft, presents with fevers and elevation of liver enzymes (AST 155, ALT 216, GGT 69, Bil 0.8). Allograft liver biopsy slide provided.

Case 10: A 5 year old child s/p liver transplant, almost 5 years ago for EHBA, now has elevated liver enzymes (AST 152, ALT 319, GGT 1395, ALKP 540, Bil 3.0). Patient's FK level is low. Allograft liver biopsy provided.

Case 11: A 6 year old boy status post multivisceral transplant, now presents with a liver mass detected on CT scan 4 years post-transplant. His liver enzymes are as follows: Bil. 5.6; AST 55; ALT 16, GGT 654. His EBV PCR was 780 copies (low). Liver mass biopsy provided.

Case 12: A 2 year old with liver and kidney transplant for polycystic disease done about a year ago presents with a viral illness in the last few weeks for which the tacrolimus levels were slightly lowered (EBV PCR 54,000). The patient is doing clinically well but was found to have elevated liver enzymes (ALT 191, AST 225). Allograft liver biopsy provided.