Whether you are a Society for Pediatric Pathology (SPP) member or a visitor, we are glad you came to explore our site. This home page will let you know what is currently going on at the SPP, what has been added to the site, what new Meetings and Events have been listed, and what new Position ads have been recently posted. The Paediatric Pathology Society (PPS) comprises our European colleagues.

What's New
NEW!!! Report from the SPP Secretary-Treasurer on the Pathology Workforce Summit held December 3, 2013, in Washington, D.C., is now online. Please click here to read more. (Updated 4/13/14)
NEW!!! 2014 SPP Spring Meeting Evaluations, SAM Post-tests, and CME/SAM Claim forms are now available. Please click here to log in. (Updated 3/2/14)
Latest SPP President's Message is now online. Please click here to read more.
Practice Committee Survey on Perinatal and Pediatric Autopsy, please click here to access.
Time to renew your SPP membership! If you haven't done so already, please click here to access.
Meeting evaluations, session materials, SAM post-tests, and CME/SAM claim forms for the 2013 SPP Fall Meeting held in Salt Lake City, Utah, September 26-29, 2013 are now available. Please click here to access.
Perspectives, Volume 28, Insights Into Pediatric Laboratory Medicine, and Volume 29, Soft Tissue Tumors in Children and Adolescents, can now be ordered online direct from Allen Press! Please click here to go to the Allen Press ordering page.

Joint Meeting of PPS and SPP
September 4-6, 2014
Birmingham UK

The Meeting Website and Meeting Registration are now OPEN.
Please click here to visit the site,
view travel information, and register to attend!

Online Abstract submission is now OPEN.
Please click here to submit your abstract today.
Abstract Submission Deadline May 31, 2014

Final Meeting Programme

Local organisers: Phil Cox, Tamas Marton and Beata Hargitai

Society for Pediatric Pathology Spring Meeting
March 1 - 2, 2014
San Diego, CA

Final Meeting Program

Meeting Abstracts

Abstract Author index

Meeting Session Materials

Evaluations, SAM Post-tests, and CME/SAM Claims

Prospective new members: Interested in joining the SPP? The New Member online registration feature is currently being upgraded and is temporarily unavailable. Please click here for a PDF Membership Application.

For more information about membership options, please click here

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Journal Watch
An eclectic selection of two dozen potentially interesting articles from current journals*

*Click here for the current watch list of journals.

All articles are in print. Please click the PMID number at the end of each citation to see the abstract on PubMed.

DISCLAIMER: Articles are listed in this section for information purposes only. The SPP does not approve or endorse these articles, and the SPP is not responsible for their content.

April 2014 Update
This month's Journal Watch prepared by Jefferson Terry, M.D., Ph.D., Hamilton, Ontario.

Click here to download April 2014 Journal Watch list.

  • Karafin MS, Humphrey RL, Detrick B. Evaluation of monoclonal and oligoclonal gammopathies in a pediatric population in a major urban center. Am J Clin Pathol. 2014 Apr;141(4):482-7. PMID: 24619747.
  • Elias S, Yamin R, Golomb L, et al. Immune evasion by oncogenic proteins of acute myeloid leukemia. Blood. 2014 123(10):1535-1534. PMID: 24449212.
  • van Bladel ER, Laarhoven AG, van der Heijden LB, et al. Functional platelet defects in children with severe chr onic ITP as tested with two novel assays applicable for low platelet counts. Blood. 2014 123(10):1556-1563. PMID: 24385537.
  • Buscarlet M, Krasteva V, Ho L, et al. Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance. Blood. 2014 Mar 13;123(11):1720-8. PMID: 24478402.
  • Vassallo PF, Simoncini S, Ligi I, et al. Accelerated senescence of cord blood endothelial progenitor cells in premature neonates is driven by SIRT1 decreased expression. Blood. 2014 Mar 27;123(13):2116-26. PMID: 24518759.
  • Hettmer S, Archer NM, Somers GR, et al. Anaplastic rhabdomyosarcoma in TP53 germline mutation carriers. Cancer. 2014 Apr 1;120(7):1068-75. PMID: 24382691.
  • Borbely AU, Daher S, Ishigai MM, et al. Decorin and biglycan immunolocalization in non-villous structures of healthy and pathological human placentas. Histopathology. 2014 Apr;64(5):616-25. PMID: 24117774.
  • Zen Y, Vara R, Portmann B, Hadzic N. Childhood hepatocellular carcinoma: a clinicopathological study of 12 cases with special reference to EpCAM. Histopathology. 2014 Apr;64(5):671-82. PMID: 24138022.
  • Na KY, Kim HS, Jung WW, et al. CXCL16 and CXCR6 in Ewing sarcoma family tumor. Hum Pathol. 2014 Apr;45(4):753-60. PMID: 24507753.
  • Tucci V, Kleefstra T, Hardy A, et al. Dominant β-catenin mutations cause intellectual disability with recognizable syndromic features. J Clin Invest. 2014 Mar 10. PMID: 24614104.
  • Kurosaka H, Iulianella A, Williams T, Trainor PA. Disrupting hedgehog and WNT signaling interactions promotes cleft lip pathogenesis. J Clin Invest. 2014 Mar 3. PMID: 24590292.
  • Viprey VF, Gregory WM, Corrias MV, et al. Neuroblastoma mRNAs Predict Outcome in Children With Stage 4 Neuroblastoma: A European HR-NBL1/SIOPEN Study. J Clin Oncol. 2014 Apr 1;32(10):1074-83. PMID: 24590653.
  • Adamski JK, Kelsey A, Brennan B. Inflammatory myofibroblastic tumors following the treatment of malignancy in childhood: case reports. J Pediatr Hematol Oncol. 2014 Mar;36(2):159-62. PMID: 23274383.
  • Taketani T, Takita J, Ueyama J, et al. Ectopic Neuroblastoma in Monozygotic Twins With Different Ages of Onset: Possible Twin-to-Twin Metastasis In Utero With Distinct Genetic Alterations After Birth. J Pediatr Hematol Oncol. 2014 Mar;36(2):166-8. PMID: 23669722.
  • Cox SG, Kilborn T, Pillay K, et al. Magnetic resonance imaging versus histopathology in Wilms tumor and nephroblastomatosis: 3 examples of noncorrelation. J Pediatr Hematol Oncol. 2014 Mar;36(2):e81-4. PMID: 23652879.
  • Sundaram SS, Sokol RJ, Capocelli KE, et al. Obstructive sleep apnea and hypoxemia are associated with advanced liver histology in pediatric nonalcoholic Fatty liver disease. J Pediatr. 2014 Apr;164(4):699-706. PMID: 24321532.
  • Molleston JP, Schwimmer JB, Yates KP, et al. Histological abnormalities in children with nonalcoholic fatty liver disease and normal or mildly elevated alanine aminotransferase levels. J Pediatr. 2014 Apr;164(4):707-713. PMID: 24360992.
  • Deshmukh H, Lioy J. The use of early lung biopsy in detection of fatal pulmonary disease in the neonate. J Pediatr. 2014 Apr;164(4):934-6. PMID: 24373577.
  • Sackmann EK, Fulton AL, Beebe DJ. The present and future role of microfluidics in biomedical research. Nature. 2014 Mar 13;507(7491):181-9. PMID: 24622198.
  • Annas GJ, Elias S. 23andMe and the FDA. N Engl J Med. 2014 Mar 13;370(11):985-8. PMID: 24520936.
  • Terashima K, Yu A, Chow WY, et al. Genome-wide analysis of DNA copy number alterations and loss of heterozygosity in intracranial germ cell tumors. Pediatr Blood Cancer. 2014 Apr;61(4):593-600. PMID: 24249158.
  • Zhou Y, Liu B, Wang M, Ni J. Endothelin-1 gene polymorphisms and risk of chemoresistant pediatric osteosarcoma. Pediatr Blood Cancer. 2014 Apr;61(4):612-7. PMID: 24123836.
  • Mossť YP, Deyell RJ, Berthold F, et al. Neuroblastoma in older children, adolescents and young adults: a report from the International Neuroblastoma Risk Group project. Pediatr Blood Cancer. 2014 Apr;61(4):627-35. PMID: 24038992.
  • Shichrur K, Feinberg-Gorenshtein G, Luria D, et al. Potential role of WSB1 isoforms in growth and survival of neuroblastoma cells. Pediatr Res. 2014 Apr;75(4):482-6. PMID: 24441107.
  • Gros J, Tabin CJ. Vertebrate limb bud formation is initiated by localized epithelial-to-mesenchymal transition. Science. 2014 Mar 14;343(6176):1253-6. PMID: 24626928.
  • Alijotas-Reig J, Llurba E, Gris JM. Potentiating maternal immune tolerance in pregnancy: A new challenging role for regulatory T cells. Placenta. 2014 Apr;35(4):241-8. PMID: 24581729.
  • Parra-Saavedra M, Crovetto F, Triunfo S, et al. Neurodevelopmental outcomes of near-term small-for-gestational-age infants with and without signs of placental underperfusion. Placenta. 2014 Apr;35(4):269-74. PMID: 24529945.
  • Georgiadis L, Keski-Nisula L, Harju M, et al. Umbilical cord length in singleton gestations: A Finnish population-based retrospective register study. Placenta. 2014 Apr;35(4):275-80. PMID: 24560495.

March 2014 Update
This month's Journal Watch prepared by Sarah L. Keating MD,University of Toronto, Toronto, Ontario.

Click here to download March 2014 Journal Watch list.

  • Gerbal-Chaloin, S., Funakoshi, N., Caillaud, A., Gondeau, C., Champon, B., & Si-Tayeb, K. (2014). Human induced pluripotent stem cells in hepatology: beyond the proof of concept. Am J Pathol, 184(2), 332-347. doi: 10.1016/j.ajpath.2013.09.026 PMID: 24269594.
  • Handa, K., Matsubara, K., Fukumitsu, K., Guzman-Lepe, J., Watson, A., & Soto-Gutierrez, A. (2014). Assembly of human organs from stem cells to study liver disease. Am J Pathol, 184(2), 348-357. doi: 10.1016/j.ajpath.2013.11.003 PMID: 24333262.
  • Huppmann, A. R., Nicolae, A., Slack, G. W., Pittaluga, S., Davies-Hill, T., Ferry, J. A., . . . Hasserjian, R. P. (2014). EBV May Be Expressed in the LP Cells of Nodular Lymphocyte-predominant Hodgkin Lymphoma (NLPHL) in Both Children and Adults. Am J Surg Pathol, 38(3), 316-324. doi: 10.1097/pas.0000000000000107 PMID: 24525501.
  • Saab, S. T., McClain, C. M., & Coffin, C. M. (2014). Fibrous hamartoma of infancy: a clinicopathologic analysis of 60 cases. Am J Surg Pathol, 38(3), 394-401. doi: 10.1097/pas.0000000000000104 PMID: 24525510.
  • Bots, M., Verbrugge, I., Martin, B. P., Salmon, J. M., Ghisi, M., Baker, A., . . . Johnstone, R. W. (2014). Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors. Blood. doi: 10.1182/blood-2013-03-488114 PMID: 24415537.
  • Steward, O., Sharp, K. G., & Matsudaira Yee, K. (2014). Long-distance migration and colonization of transplanted neural stem cells. Cell, 156(3), 385-387. doi: 10.1016/j.cell.2014.01.017 PMID: 24485444.
  • Cakir, I., & Ozcan, U. (2014). Mom's Milk Molds Neural Wiring for Metabolism. Cell, 156(3), 396-397. doi: 10.1016/j.cell.2014.01.033 PMID: 24485448.
  • Puls, F., Niblett, A. J., & Mangham, D. C. (2014). Molecular pathology of bone tumours: diagnostic implications. Histopathology, 64(4), 461-476. doi: 10.1111/his.12275 PMID: 24428620.
  • Hansson, J., Hultenby, K., Cramnert, C., Ponten, F., Jansson, H., Lindgren, D., . . . Johansson, M. E. (2014). Evidence for a morphologically distinct and functionally robust cell type in the proximal tubules of human kidney. Hum Pathol, 45(2), 382-393. doi: 10.1016/j.humpath.2013.10.003 PMID: 24439225.
  • Rexhaj, E., Paoloni-Giacobino, A., Rimoldi, S. F., Fuster, D. G., Anderegg, M., Somm, E., . . . Scherrer, U. (2013). Mice generated by in vitro fertilization exhibit vascular dysfunction and shortened life span. J Clin Invest, 123(12), 5052-5060. doi: 10.1172/jci68943 PMID: 24270419.
  • Lim, B. K., Peter, A. K., Xiong, D., Narezkina, A., Yung, A., Dalton, N. D., . . . Knowlton, K. U. (2013). Inhibition of Coxsackievirus-associated dystrophin cleavage prevents cardiomyopathy. J Clin Invest, 123(12), 5146-5151. doi: 10.1172/jci66271 PMID: 24200690.
  • Riehle, C., Wende, A. R., Sena, S., Pires, K. M., Pereira, R. O., Zhu, Y., . . . Abel, E. D. (2013). Insulin receptor substrate signaling suppresses neonatal autophagy in the heart. J Clin Invest, 123(12), 5319-5333. doi: 10.1172/jci71171 PMID: 24177427.
  • Stadler, Z. K., Schrader, K. A., Vijai, J., Robson, M. E., & Offit, K. (2014). Cancer genomics and inherited risk. J Clin Oncol, 32(7), 687-698. doi: 10.1200/jco.2013.49.7271 PMID: 24449244.
  • Mueller, E. L., Park, E. R., & Davis, M. M. (2014). What the affordable care act means for survivors of pediatric cancer. J Clin Oncol, 32(7), 615-617. doi: 10.1200/jco.2013.52.6467 PMID: 24395862.
  • Wilmott, R. W. (2014). Repeat hospitalizations for childhood asthma. J Pediatr, 164(2), 223- 225. doi: 10.1016/j.jpeds.2013.11.051 PMID: 24461146.
  • Dai, S., Yang, Q., Yuan, K., Loustalot, F., Fang, J., Daniels, S. R., & Hong, Y. (2014). Non- high-density lipoprotein cholesterol: distribution and prevalence of high serum levels in children and adolescents: United States national health and nutrition examination surveys, 2005-2010. J Pediatr, 164(2), 247-253. doi: 10.1016/j.jpeds.2013.08.069 PMID: 24139441.
  • Robertson, B. D., Lang, C., & Bachim, A. (2014). At-risk children of at-risk parents: assessing common injuries to the children of teenage parents. J Pediatr, 164(2), 347-351 e341. doi: 10.1016/j.jpeds.2013.09.024 PMID: 24238858.
  • Polo-Kantola, P., Lampi, K. M., Hinkka-Yli-Salomaki, S., Gissler, M., Brown, A. S., & Sourander, A. (2014). Obstetric risk factors and autism spectrum disorders in Finland. J Pediatr, 164(2), 358-365. doi: 10.1016/j.jpeds.2013.09.044 PMID: 24183209.
  • Kim, B. E., Koh, K. N., Suh, J. K., Im, H. J., Song, J. S., Lee, J. W., . . . Seo, J. J. (2014). Clinical features and treatment outcomes of langerhans cell histiocytosis: a nationwide survey from Korea histiocytosis working party. J Pediatr Hematol Oncol, 36(2), 125-133. doi: 10.1097/mph.0000000000000054 PMID: 24276037.
  • Chemotherapy, immunity and microbiota-a new triumvirate? (2014). Nat Med, 20(2), 126-127. doi: 10.1038/nm.3473 PMID: 24504404.
  • Bianchi, D. W., Parker, R. L., Wentworth, J., Madankumar, R., Saffer, C., Das, A. F., . . . Sehnert, A. J. (2014). DNA sequencing versus standard prenatal aneuploidy screening. N Engl J Med, 370(9), 799-808. doi: 10.1056/NEJMoa1311037. PMID: 24571752.
  • D'Acremont, V., Kilowoko, M., Kyungu, E., Philipina, S., Sangu, W., Kahama-Maro, J., . . . Genton, B. (2014). Beyond malaria--causes of fever in outpatient Tanzanian children. N Engl J Med, 370(9), 809-817. doi: 10.1056/NEJMoa1214482. PMID: 24571753.
  • Turner, K. M., Lee, H. C., Boppana, S. B., Carlo, W. A., & Randolph, D. A. (2014). Incidence and Impact of CMV Infection in Very Low Birth Weight Infants. Pediatrics. doi: 10.1542/peds.2013-2217. PMID: 24488749.
  • Dobrozsi, S., Flood, V. H., Panepinto, J., Scott, J. P., & Brandow, A. (2014). Vitamin B12 deficiency: The great masquerader. Pediatr Blood Cancer, 61(4), 753-755. doi: 10.1002/pbc.24784 PMID: 24115632.

Click here for previous journal watch listings.

From the Editor's Desk

Dear Colleagues:

Salutations! The SPP Spring Meeting, to be held in San Diego, CA, on March 1 and 2, 2014, is approaching. Links to meeting registration, hotel and travel information, and the preliminary program are now available by clicking here.

Have you been using Journal Watch? It is a handy overview of recent literature prepared every month by members of the SPP Research Committee. Please see the latest Journal Watch by clicking here.

Robert E Ruiz
SPP Website Editor

Questions and comments about website content can be directed to the website editor. Technical concerns can be directed to the site webmaster.